Headache for Canadian Medical Students
Introduction
Headache is a common presenting complaint in Canadian primary care and emergency settings. As a future Canadian physician preparing for the MCCQE1, understanding the various types of headaches, their presentations, and management strategies is crucial. This guide will focus on the most important aspects of headache diagnosis and treatment in the Canadian healthcare context, aligning with MCCQE1 objectives and the CanMEDS framework.
This guide is designed to help you prepare for the MCCQE1 exam, focusing on headache-related topics that are highly relevant to Canadian medical practice.
Types of Headaches
Headaches are broadly classified into two categories: primary and secondary. Understanding this classification is essential for MCCQE1 preparation.
- Migraine
- Tension-type headache
- Cluster headache
- Other trigeminal autonomic cephalalgias
Migraine
Migraine is a common primary headache disorder affecting approximately 2.7 million Canadians. Understanding its presentation and management is crucial for MCCQE1 success.
Diagnostic Criteria (ICHD-3)
For MCCQE1 preparation, memorize these criteria:
- At least 5 attacks fulfilling criteria 2-4
- Headache attacks lasting 4-72 hours (untreated or unsuccessfully treated)
- Headache has at least two of the following characteristics:
- Unilateral location
- Pulsating quality
- Moderate or severe pain intensity
- Aggravation by or causing avoidance of routine physical activity
- During headache, at least one of the following:
- Nausea and/or vomiting
- Photophobia and phonophobia
In Canada, migraine prevalence is higher in women (12%) compared to men (4%), which is important to consider when assessing patients in clinical scenarios on the MCCQE1.
Management
Step 1: Acute Treatment
- First-line: NSAIDs or acetaminophen
- Second-line: Triptans (e.g., sumatriptan)
Step 2: Preventive Treatment
Consider if:
- ≥4 migraine days/month
- Significant disability despite acute treatment
- Contraindication to acute treatments
Options include:
- Beta-blockers (e.g., propranolol)
- Anticonvulsants (e.g., topiramate)
- Antidepressants (e.g., amitriptyline)
- CGRP antagonists (e.g., erenumab)
Step 3: Non-pharmacological Approaches
- Lifestyle modifications
- Stress management
- Cognitive Behavioral Therapy (CBT)
Tension-Type Headache
Tension-type headache is the most common primary headache disorder. Its recognition and management are important for MCCQE1 preparation.
Diagnostic Criteria (ICHD-3)
- At least 10 episodes fulfilling criteria 2-4
- Headache lasting from 30 minutes to 7 days
- At least two of the following characteristics:
- Bilateral location
- Pressing or tightening (non-pulsating) quality
- Mild or moderate intensity
- Not aggravated by routine physical activity
- Both of the following:
- No nausea or vomiting
- No more than one of photophobia or phonophobia
Management
- Acute treatment: NSAIDs or acetaminophen
- Preventive treatment: Amitriptyline if chronic
- Non-pharmacological: Stress management, physical therapy
Cluster Headache
Cluster headache is a severe primary headache disorder that's important to recognize for the MCCQE1 exam.
Diagnostic Criteria (ICHD-3)
- At least 5 attacks fulfilling criteria 2-4
- Severe or very severe unilateral orbital, supraorbital and/or temporal pain lasting 15-180 minutes (when untreated)
- Either or both of the following:
- At least one of the following symptoms or signs, ipsilateral to the headache:
- Conjunctival injection and/or lacrimation
- Nasal congestion and/or rhinorrhea
- Eyelid edema
- Forehead and facial sweating
- Forehead and facial flushing
- Sensation of fullness in the ear
- Miosis and/or ptosis
- A sense of restlessness or agitation
- At least one of the following symptoms or signs, ipsilateral to the headache:
- Occurring with a frequency between one every other day and 8 per day
Management
- Acute treatment: Oxygen therapy, sumatriptan injection or nasal spray
- Preventive treatment: Verapamil, lithium, or topiramate
Red Flags for Secondary Headaches
For MCCQE1 preparation, memorize these red flags that suggest a secondary headache:
- Sudden-onset severe headache ("thunderclap")
- New headache after age 50
- Progressively worsening headache
- Headache associated with systemic symptoms (fever, weight loss)
- Headache with focal neurological signs
- Headache triggered by position change or Valsalva maneuver
- Headache in an immunocompromised patient
Presence of any red flags warrants immediate further investigation, typically including neuroimaging.
Canadian Guidelines for Headache Management
The Canadian Headache Society provides guidelines for headache management, which are essential to know for the MCCQE1:
- Use validated screening tools for migraine diagnosis in primary care
- Consider prophylaxis for patients with ≥4 migraine days/month
- Educate patients on medication overuse headache risk
- Refer to a headache specialist if standard treatments fail or diagnosis is uncertain
Key Points to Remember for MCCQE1
- Know the diagnostic criteria for primary headaches (migraine, tension-type, cluster)
- Understand the red flags suggesting secondary headaches
- Be familiar with Canadian guidelines for headache management
- Recognize the importance of non-pharmacological approaches in headache management
- Understand the role of neuroimaging in headache evaluation
- Be aware of medication overuse headache as a complication of frequent analgesic use
Sample Question
A 35-year-old woman presents to her family physician with a 6-month history of recurrent headaches. She describes the pain as bilateral, pressing, and of moderate intensity, lasting 2-3 hours. The headaches occur 3-4 times per week and are not associated with nausea, vomiting, or sensitivity to light or sound. Physical examination is normal. Which one of the following is the most likely diagnosis?
- A. Migraine without aura
- B. Cluster headache
- C. Tension-type headache
- D. Medication overuse headache
- E. Chronic daily headache
Explanation
The correct answer is:
- C. Tension-type headache
This patient's presentation is classic for tension-type headache:
- Bilateral location
- Pressing quality
- Moderate intensity
- No associated symptoms like nausea, vomiting, photophobia, or phonophobia
- Duration within the typical range for tension-type headache (30 minutes to 7 days)
Migraine typically involves unilateral, pulsating pain with associated symptoms. Cluster headache presents with severe unilateral pain and autonomic symptoms. Medication overuse headache requires a history of frequent analgesic use. Chronic daily headache is a descriptive term, not a specific diagnosis.
References
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Headache Classification Committee of the International Headache Society (IHS). The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018;38(1):1-211.
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Becker WJ, Findlay T, Moga C, Scott NA, Harstall C, Taenzer P. Guideline for primary care management of headache in adults. Can Fam Physician. 2015;61(8):670-679.
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Worthington I, Pringsheim T, Gawel MJ, et al. Canadian Headache Society Guideline: acute drug therapy for migraine headache. Can J Neurol Sci. 2013;40(5 Suppl 3):S1-S80.
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Peng KP, Wang SJ. Epidemiology of headache disorders in the Asia-pacific region. Headache. 2014;54(4):610-618.
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Katsarava Z, Buse DC, Manack AN, Lipton RB. Defining the differences between episodic migraine and chronic migraine. Curr Pain Headache Rep. 2012;16(1):86-92.